Advances in local targeted gene therapy for arthritis: towards clinical reality

Margriet J Vervoordeldonk, Caroline J Aalbers & Paul P Tak† †Author for correspondence Academic Medical Center/University of Amsterdam, Division of Clinical Immunology and Rheumatology, F4–218, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands Tel.: +31 205 662 171; Fax: +31 206 919 658; p.p.tak@amc.uva.nl and, Arthrogen BV, Amsterdam, The Netherlands ‘[There is] a strong rationale for IFN-β gene therapy as a novel therapeutic approach for arthritis.’